Mediators of Lung damage and Dysfunction in Tuberculosis

TB is caused by the bacterium M tuberculosis. The infection in the lungs damages the lung tissue causing them to cough up the bacteria which then spread through the air and can be inhaled and exhaled by the others. In the complete damages of lung tissues which results in large holes in the lung lobes called cavities and widening of the airways called bronchiectasis.

The healing process after treatment of tuberculosis can cause damage as loss of the spongy part of the lung ultimately leading to restrictive spirometry or restrictive lung disease. Pulmonary TB is curable with treatment but if not treated properly and treatment left behind negligence the disease often causes life-threatening concerns. Untreated pulmonary TB disease can lead to long-term damage to these lungs.

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